AACR 2015: What’s New in NCI’s Center for Cancer Genomics: An Overview of Programs

Monday, April 20, 2015, 1:30 PM - 3:30 PM
Room 105, Pennsylvania Convention Center, Philadelphia, Pa.

The NCI Center for Cancer Genomics (CCG) is innovating across the entire spectrum of cancer genomics: from basic cancer genomics research, development of bioinformatics infrastructure to improve data accessibility, to validating new therapeutic targets and diagnostic and prognostic markers. The Center for Cancer Genomics supports research in different fields of cancer genomics – structural, functional and computational – with the goal of advancing precision medicine and ultimately improving patient outcomes. 

In this session, we will describe initiatives supported by the CCG including programmatic objectives and research highlighting the data, resources and tools available to the research community from each program. The speakers will provide updates on the tumor characterization initiatives in both adult and pediatric cancers including the Burkitt Lymphoma Genome Sequencing Project (BLGSP), HIV+ Tumor Molecular Characterization Project (HTMCP), Therapeutically Applicable Research to Generate Effective Treatments (TARGET), and The Cancer Genome Atlas (TCGA). Newer CCG programs will also be featured to include Cancer Driver and Development Program (CDDP), The Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trials (ALCHEMIST), and the Exceptional Responders Initiative. The session will report on the Cancer Target Development and Discovery (CTD2) initiative which seeks to bridge the gap between the enormous volumes of data generated by the genomic characterization studies and the ability to use these data for the development of human cancer therapeutics. In the future, the comprehensive genomic data generated by CCG initiatives will be made available to the research community through the Genomic Data Commons (GDC), which will be outlined together with the related NCI Cancer Genomics Cloud Pilots managed through CBIIT (NCI Center for Bioinformatics and Information Technology). Together these platforms will allow for analytic tools to be leveraged that can effectively compute over the genomics data. Finally, the new CCG website will be presented.

  • Jaime Guidry Auvil. National Cancer Institute, Bethesda, Md.
  • Jean C. Zenklusen. National Cancer Institute, Bethesda, Md.
  • Roy Tarnuzzer. National Cancer Institute, Bethesda, Md.
  • Subhashini Jagu. Johns Hopkins University School of Medicine, Baltimore, Md.
  • Zhining Wang. National Cancer Institute, Bethesda, Md.
  • Tanja M. Davidsen. National Cancer Institute, Bethesda, Md.
  • Emma J. Spaulding. National Cancer Institute, Bethesda, Md.

For more information, please visit the AACR website