TCGA Analysis of Liver Cancer
Researchers in The Cancer Genome Atlas (TCGA) Research Network performed an integrative study of 196 liver cancer genomes and identified targets for therapies that are currently available or under development.
TCGA Study of Cholangiocarcinoma
Investigators with The Cancer Genome Atlas (TCGA) Research Network characterized 58 cholangiocarcinomas, rare cancers of bile ducts, and identified a new subtype characterized by mutation of the IDH gene.
Cancers Selected for Study
The Cancer Genome Atlas researchers are mapping the genetic changes in 33 cancers. Find out which cancers have been selected for study, the criteria for selection and the scientific questions being asked about each cancer.
Program Overview
Explore how The Cancer Genome Atlas works, the components of the TCGA Research Network and TCGA's place in the cancer genomics field in the Program Overview.
Cancers Selected for Study
About TCGA
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TCGA in Action
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December 2016
CASE STUDY: A Researcher Mined TCGA Data to Study Her Own Ovarian Cancer
Faced the bleak prognosis associated with stage IIIC ovarian cancer, Shirley Pepke, Ph.D., used her computational biology background to study her own cancer in comparison to TCGA data. Pepke has now been in remission for a year. Image Credit: Gus Ruelas/USC -
September 2016
CASE STUDY: TCGA Data Leveraged for Developing FDA-Designated Breakthrough Therapy
Pharmaceutical company Loxo Oncology used TCGA data in the research that led them to develop FDA-designated Breakthrough Therapy LOXO-101, a promising new targeted therapy.
More Stories
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News and Announcements
- June 15, 2017
TCGA study of liver cancer reveals potential targets for therapy
Researchers in The Cancer Genome Atlas (TCGA) Research Network performed an integrative study of 196 liver cancer genomes and identified targets for therapies that are currently available or under development. - March 14, 2017
TCGA Investigators Improve Understanding of the Molecular Drivers of Cholangiocarcinoma
Investigators with The Cancer Genome Atlas (TCGA) Research Network characterized 58 cholangiocarcinomas, rare cancers of bile ducts, and identified a new subtype characterized by mutation of the IDH gene.
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Research Briefs
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June 2017
TCGA Data Used to Study Ties Between Tumor Genetics and Evolutionary History
A study using TCGA data investigated the theory that cancer cells revert to ancient cellular processes. The researchers found repression of newer cellular processes and activation of older genes, providing insight into the hallmarks of cancer common across different types.
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Perspectives
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October 2015
Genomic Contributions to Breast Cancer Disparities
Dr. Tanya Keenan shares her study's findings on the genomic contributions to breast cancer disparities and advocates for inclusion in breast cancer research.
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