• National Cancer Institute
  • National Human Genome Research Institute


Posted: April 30, 2014

The ICGC-TCGA DREAM Somatic Mutation Calling (SMC) Challenge

The Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC), in collaboration with Sage Bionetworks and IBM-DREAM, recently launched the ICGC-TCGA DREAM Somatic Mutation Calling (SMC) Challenge. The SMC Challenge is an open, crowd-sourced initiative to identify the most accurate and robust methods for detecting cancer-associated mutations in whole-genome sequencing data. These techniques will hopefully become the standard approaches for analyzing cancer genomic data in both research and clinical practice. Algorithms from participating teams will use real data and their performance will be assessed independently. The winning algorithms will be included in publications with Nature Publishing Group and may help advance the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes project, the next Pan-Cancer effort analyzing whole-genome sequencing data currently underway. For more information, please visit the ICGC-TCGA DREAM Somatic Mutation Calling Challenge website.