Protein Characterization Centers (PCCs) are part of NCI’s Clinical Proteome Tumor Analysis Consortium (CPTAC) and work with The Cancer Genome Atlas (TCGA) to characterize the proteome of TCGA samples. This additional information adds another dimension to TCGA’s already multi-faceted data. On September 4, 2013, CPTAC released the proteomic data generated from TCGA’s colorectal cancer samples, which were published in Nature in 2012. This announcement follows five years of research, during which the foundation was laid for this data production step. Thanks to the collaboration between CPTAC and TCGA, PCCs have generated proteomic data from 90 colorectal tumors. The additional genomic information available through the TCGA Data Portal and CGHub makes these proteomics data the first of its kind.
A blog post from CPTAC’s program manager, Chris Kinsinger Ph.D., can be found here.
The CPTAC Data Portal can be found here.
More information about the PCCs’ role in TCGA can be found here.