The Cancer Genome Atlas (TCGA) Research Network is providing data and genome analysis to the cancer research community which is supporting new discoveries and accelerating the pace of cancer research. Below is a list of selected articles that describe the broad impact of TCGA on cancer research.
- January 19, 2010
TCGA Identifies Distinct Subtypes of Deadly Brain Cancer That May Lead to New Treatment Strategies
TCGA researchers identified four distinct molecular subtypes of glioblastoma multiforme (GBM), and demonstrated that response to aggressive chemotherapy and radiation differed by subtype.
- December 22, 2009
Children's Hospital Major Player in Tumor War
The Research Institute at Nationwide Children’s Hospital is selected as one of two Biospecimen Core Resources for TCGA tumor collection. Thousands of samples from 250 hospitals in the United States and other countries will be sent to the Columbus-based institution for potential use in TCGA research.
- December 01, 2009
Program Looks for Genetic Markers of Cancer
Community cancer centers play a critical role in the success of TCGA. Since community cancer centers see the majority of cancer patients, they are instrumental in consenting patients to donate their tissue to the TCGA program so that researchers can identify the genomic changes in these cancers.
- December 01, 2009
Recovery Act Investment in TCGA Creates Prospective Tissue Accrual Network
Thanks to the investment of Recovery Act funds, the ability to obtain the quality and quantity of biospecimens required for TCGA will be significantly improved and the pace of TCGA research accelerated through the creation of a prospective tissue accrual network.
- November 27, 2009
ASCO Report: Clinical Cancer Advances 2009
The American Society of Clinical Oncology (ASCO) issued its Clinical Cancer Advances 2009. TCGA findings on the genetics of glioblastoma are highlighted as a notable advance in nervous system cancers.
- November 23, 2009
Christiana Care’s Cancer Center First Community Hospital to Submit Samples to Genome Project
Christiana Care Health System's Helen F. Graham Cancer Center became the first community hospital in the nation to submit specimens to the Biospecimen Core Resource of TCGA.
- November 13, 2009
Genetics Offers Promise of Personalized Medicine
An NIH-wide look at the role genomics is playing in personalized medicine includes an interview with Anna D. Barker, Ph.D., former NCI Deputy Director, who discusses TCGA’s contribution to enabling a more personalized approach to cancer care.
- October 09, 2009
Looking for a Target on Every Tumor
The practice of genotyping patient tumors is increasing among major cancer centers with the hope of matching drugs to genetic targets to stop cancer's growth. Read about the promise and challenges of targeted therapies and the role of TCGA. Transcript
- September 24, 2009
National Brain Tumor Society Awards TCGA Research Network
The National Brain Tumor Society (NBTS) presented its first Founders Award for Research Excellence jointly to The Cancer Genome Atlas Research Network and the Johns Hopkins Kimmel Cancer Center/Duke University Medical Center Group. The award, which is presented to research teams whose investigations hold promise for clinical improvements, recognized the ground-breaking work of these two initiatives in the “major collective advancement in the genomic analysis of gliomas”.
- April 01, 2009
Genomics vs. Cancer
This article reviews how large scale genomics projects like TCGA and the Tumor Sequencing Project are examples of innovative research that demonstrate why scientists can no longer rely on a single type of technology for discovery.