The Cancer Genome Atlas (TCGA) Research Network is providing data and genome analysis to the cancer research community which is supporting new discoveries and accelerating the pace of cancer research. Below is a list of selected articles that describe the broad impact of TCGA on cancer research.
- August 04, 2011
Analyzing the Genetic Makeup of Ovarian Cancer
Dr. Douglas Levine, a physician and researcher at Memorial Sloan-Kettering Cancer Center, discusses the impact of understanding cancer genetics as it relates to a patient's care.
- November 30, 2010
Researchers Discover Key Mutation in Acute Myeloid Leukemia
Tim Ley, M.D., Washington University researcher, discusses the importance of a key mutation found in acute myeloid leukemia. This mutation may be an important tool to classify patients for treatment.
- November 12, 2010
Mutations in Single Gene Predict Poor Outcomes in Adult Leukemia
Washington University School of Medicine researchers discover a gene found to be commonly altered in many patients who died quickly of the disease.
- August 11, 2010
Francis Collins: One Year at the Helm
Francis Collins, Ph.D., marks his one-year anniversary as the National Institutes of Health (NIH) director. This Nature article addresses his accomplishments to date, including his investment in TCGA, and the challenges he faces ahead.
- August 01, 2010
Fostering Groundbreaking Medical Research: Investments in the National Institutes of Health
The White House reports on how Recovery Act funds are enabling groundbreaking research at NIH, including genomic mapping of 20 cancers through the TCGA project.
- April 06, 2010
House Committee Convenes Hearing on NCI Research
Former NCI Deputy Director Dr. Anna Barker testified before the House of Representatives Committee on Energy and Commerce, Subcommittee on Health at a hearing held on March 23. Focusing on progress in molecular biology and advanced technologies, Dr. Barker provided an overview of TCGA emphasizing that the biggest challenge to expanding TCGA is obtaining high-quality biospecimens.
- February 09, 2010
Cancer Bulletin Profile: Meet Dr. Raju Kucherlapati
The Cancer Bulletin profiles Raju Kucherlapati, Ph.D., a Paul C. Cabot Professor of Genetics and Professor of Medicine at Harvard Medical School, and a principal investigator for TCGA. Dr. Kucherlapati is working toward characterizing the genetic and genomic changes found in cancer samples with the goal of understanding how cancer develops and to identify meaningful subtypes of cancer in order to determine which drugs are most likely to work.
- January 28, 2010
CBS Where America Stands: Cancer
NIH Director, Dr. Francis Collins, is interviewed by Katie Couric on CBS Evening News, Jan. 28, drawing upon the discoveries being made by TCGA researchers to improve cancer treatments.
- January 26, 2010
Brain Cancer, Like Other Cancers, Has Distinct Subtypes
Molecular findings are presenting new avenues for brain cancer treatment. This article references TCGA's research defining four subtypes of glioblastoma that respond differently to therapy.
- January 25, 2010
In Tough Economic Times, NIH Head Looks to Clinic
NIH Director, Dr. Francis Collins, discusses his plans for NIH and how programs like TCGA will bring different approaches to cancer treatments.