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The Cancer Genome Atlas

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Pilot Project To Map Three Cancers
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Map of TCGA Components
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www.cancer.gov National Cancer Institute National Human Genome Research Institute

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The Cancer Genome Atlas (TCGA), a three-year pilot project of the National Cancer Institute and the National Human Genome Research Institute, is a large-scale collaborative effort to understand the genomic changes that occur in cancer. TCGA involves a broad cross-section of the cancer research community, including basic and clinical researchers, clinicians, and patient advocates.

TCGA is unique in the benefits and advantages that it provides to cancer research, as it was designed to allow the integration of clinical, genomic characterization, and large-scale genomic sequencing data of all samples. TCGA researchers characterize and sequence the genomes of up to 500 samples of both tumor and matched normal tissues for each of three selected cancer types: brain (glioblastoma multiforme), lung (squamous carcinoma), and ovarian (serous cystadenocarcinoma).

New data derived from TCGA analyses will be deposited on a regular basis into databases, which can be accessed from this page. These data include:

  1. Clinical information associated with cancer tumors and human subjects,
  2. Genomic characterization, and
  3. High-throughput sequencing analysis of the tumor genomes.
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