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| TCGA Publications
 Scientific Publications
Brochures
TCGA Reports
Policy Documents
Scientific Publications
All data generated by the TCGA Resesarch Network is made open to the public through the Data Coordinating Center and the TCGA Data Portal. The following is a growing list of publications from the TCGA Research Network (designated with an *) and from other investigators who have successfully leveraged the TCGA data for their own work.
Bredel, M., Scholtens, D.M., Harsh, G.R., Bredel, C., Chandler, J.P., Renfrow, J.J., Yadav, A.K., Vogel, H., Scheck, A.C., Tibshirani, R., et al. (2009). A Network Model of a Cooperative Genetic Landscape in Brain Tumors. JAMA 302, 261-275.
Wrensch, M., Jenkins, R. B., Chang, J. S., Yeh, R., Xiao, Y., Decker, P. A., Ballman, K. V., Berger, M., Buckner, J. C., Chang, S., et al (2009). Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility. Nature Genetics published online 5 July 2009.
Shete, S., Hosking, F. J., Robertson, L. B., Dobbins, S. E., Sanson, M., Malmer, B., Simon, M., Marie, Y., Boisselier, B., Delattre, J., et al (2009). Genome-wide association study identifies five susceptibility loci for glioma. Nature Genetics published online 5 July 2009.
Veeriah, S., Brennan, C., Meng, S., Singh, B., Fagin, J.A., Solit, D.B., Paty, P.B., Rohle, D., Vivanco, I., Chmielecki, J., et al. (2009). The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers. Proc Natl Acad Sci U S A 106, 9435-9440.
Bengtsson, H., Ray, A., Spellman, P., and Speed, T.P. (2009). A single-sample method for normalizing and combining full-resolution copy numbers from multiple platforms, labs and analysis methods. Bioinformatics 25, 861-867.
Li, A., Walling, J., Ahn, S., Kotliarov, Y., Su, Q., Quezado, M., Oberholtzer, J.C., Park, J., Zenklusen, J.C., and Fine, H.A. (2009). Unsupervised analysis of transcriptomic profiles reveals six glioma subtypes. Cancer Res 69, 2091-2099.
Hampton, O.A., Den Hollander, P., Miller, C.A., Delgado, D.A., Li, J., Coarfa, C., Harris, R.A., Richards, S., Scherer, S.E., Muzny, D.M., et al. (2009). A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome. Genome Res 19, 167-177.
Chiang, D.Y., Getz, G., Jaffe, D. B., O’Kelly, M.J., Zhao, X., Carter, S.L., Russ, C., Nusbaum, C., Meyerson, M., and Lander, E.S. (2009). High-resolution mapping of copy-number alterations with massively parallel sequencing. Nat Methods 6, 99-103.
Freire, P., Vilela, M., Deus, H., Kim, Y.-W., Koul, D., Colman, H., Aldape, K.D., Bogler, O., Yung, W.K.A., Coombes, K., et al. (2008). Exploratory Analysis of the Copy Number Alterations in Glioblastoma Multiforme. PLoS One 3, Article No.: e4076.
Zheng, H., Ying, H., Yan, H., Kimmelman, A.C., Hiller, D.J., Chen, A.J., Perry, S.R., Tonon, G., Chu, G.C., Ding, Z., et al. (2008). p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature 455, 1129-1133.
*The Cancer Genome Atlas Research Network. (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455, 1061-1068.
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Brochures
The Cancer Genome Atlas (TCGA) Brochure
Charting a New Course for Prevention, Diagnosis, and Treatment of Cancer
The Cancer Genome Atlas Pilot Project brochure is designed for the public and describes
some aspects of cancer development and the Pilot Project. The brochure summarizes
information on the cancers being studied, the components of the Pilot Project, and
long term goals for the Atlas, including improvement of cancer diagnosis, treatment,
and prevention.
Click here to view the TCGA brochure.
The Cancer Genome Atlas Data Portal Brochure
Navigating the Data Portal
The Cancer Genome Atlas Data Portal brochure provides information on how the data portal works, how to access and analyze data, featured tools, responsible data use and how TCGA will benefit cancer research and patients.
Click here to view the TCGA Data Portal brochure.
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TCGA Reports
In the course of developing The Cancer Genome Atlas Pilot Project, the National
Cancer Institute and the National Human Genome Research Institute have received
input from some of the world’s leading experts in areas such as cancer genomics,
bioinformatics, microarray technologies, and bioethics, as well as members of the
patient advocacy community. The reports received by NCI and NHGRI are available
below.
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Policy Documents
In maintaining responsible data use practices for TCGA and using consistent publication
practices as data becomes more readily available, TCGA’s leading experts have released
a new TCGA data use policy and publications guide. The data use policy and publishing
guidelines are available below:
The Responsible Use and Publication of Data Generated
by the TCGA Pilot Project
Publication Guidelines for Members of the TCGA Network
Click here if you would like to return to Media Center
Overview.
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